Understanding Anxiety, Depression, and Panic Disorders
Anxiety, depression and panic disorders are pervasive and debilitating chronic mental health conditions, affecting approximately 20% of the global population over a lifetime. These disorders are among the most prevalent mental health conditions globally, affecting millions and imposing a substantial burden on individuals, families, and healthcare systems.
While current treatment options include pharmacotherapy and cognitive-behavioral therapy, response rates vary, and many patients experience residual symptoms or adverse effects, leading to high rates of treatment discontinuation. Furthermore, the growing recognition of treatment-resistant anxiety and panic disorders highlights an urgent need for innovative, evidence-based therapies that provide sustained relief without compromising safety.
Despite the availability of pharmacotherapy, such as selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines, alongside cognitive-behavioral therapy (CBT), there remain substantial challenges in achieving and maintaining symptom relief. Response rates to these standard treatments vary widely, and a significant proportion of patients experience partial or inadequate relief, with some exhibiting treatment-resistant symptoms. Moreover, pharmacological treatments can be associated with side effects like weight gain, fatigue, and cognitive impairment, which may lead to discontinuation or non-adherence. These limitations highlight a critical need for alternative or adjunctive interventions that can provide more effective, sustainable, and safer outcomes.
The exact etiology of anxiety, depression and panic disorder remained unclear. This underscores the need for a more comprehensive understanding of the underlying mechanisms of anxiety and the development of more effective treatments. The current study aims to investigate the etiology of anxiety, depression and panic disorders, and address gaps in existing treatments for anxiety and panic disorders.
Findings from this study are anticipated to advance clinical understanding and treatment options for anxiety and panic disorders, providing a potentially more effective approach and novel treatments that provide lasting relief for patients struggling with these conditions.
Objectives: This study aims to investigate the etiology of anxiety depression and panic disorders, providing new evidence and insights into the root causes of these disorders, potentially offering a novel approach to achieving complete recovery for patients.
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